what you really want is to become as tanky as possible.
voodoo shuffle and astral shift are your friends, second glyph should be whatever heals you more between the regen and the lifesteal.
get items with flat damage reduction/reduction based on agility first. order isn’t too important, because once you’re at a certain baseline of durability you just need the attack/crit boosting items and your lifesteal will become bonkers.
its been a while so a lot of the so specifics escape me, but here’s my promise; the early game will comprise the bulk of the time you spend on this run, because you’ll have to do very cowardly, time consuming things to clear mobs and once you start getting tanky items and levels everything becomes a trash mob
determination leads u to ultimate power. that and skull splitting snakes for hours.